Reviving Tired T Cells to Improve Immuno-Oncology Treatments
June 18, 2019
By Neozene

A population of immune cells known as effector T cells are important in the fight against cancer and infectious diseases, because they produce substances that kill the pathogenic cells. Problem is, these T cells can become exhausted. A team at the University of Pennsylvania has discovered a protein that helps determine the fate of exhausted T cells—and that might be able to be targeted to improve immuno-oncology treatments. The protein, called TOX, controls the evolution of exhausted T cells. Specifically, high levels of TOX sustained over a long period of

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ADA: Insulet Sees Gains in Type 1 Diabetes Study With Tubeless Insulin Pump in Young Children
June 11, 2019
By Neozene

Insulet presented new data evaluating the use of its tubeless, closed-loop Omnipod insulin management system in young children with Type 1 diabetes. Using an investigational version of the device, 14 children between the ages of two and six were supervised for over a week in a hotel to simulate the unique challenges of an at-home setting for this age group. Following seven days of standard therapy with continuous glucose monitoring, the participants entered a two- to three-day treatment phase using the Omnipod’s personalized, predictive algorithms. During this second phase, meals

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Flow launches at-home depression headset and therapy app in the U.K.
June 4, 2019
By Neozene

Swedish medical device developer Flow Neuroscience has launched its at-home, wearable treatment for adults with depression, available for purchase and use in the U.K. Paired with a behavioral therapy app, Flow’s headset delivers low levels of constant direct brain stimulation aimed at the user’s left frontal lobe. According to the company, people diagnosed with depression often have lower neural activity in this region of the brain, which helps govern certain cognitive skills and emotional expression. By rebalancing that activity, Flow hopes to offer similar outcomes compared to typical antidepressant drugs, and

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