‘Nano-Immunotherapy’ Halts Glioblastoma in Mice
August 29, 2019
By Neozene

This article originally appeared in FierceBiotech and was written by Arlene Weintraub One of the most difficult challenges in treating the brain cancer glioblastoma is that few drugs can pass through the blood-brain barrier. Scientists at Cedars-Sinai in Los Angeles have developed a system to circumvent this hurdle—one that combines a powerful immuno-oncology drug with a polymer-based delivery vehicle that can cross the blood-brain barrier. The researchers showed that this “nano-immunotherapy” treatment crossed the blood-brain barrier in mouse models of glioblastoma, and that it stopped tumor cells from multiplying. They

Read More

Restoring Neurons to Preserve Memory After Heart Attack or Stroke
August 21, 2019
By Neozene

This article originally appeared in FierceBiotech and was written by Arlene Weintraub People who suffer from heart attacks or strokes face a high risk of memory loss, because when fresh blood stops flowing in the brain, neurons in a region of the hippocampus involved in memory can die. Now, Stanford University researchers are proposing a new strategy for helping the brain recover those brain cells—and it involves controlling the activation of genes that can coax surrounding cells to transform into neurons. The team showed that blocking a particular microRNA in

Read More

Ebola Meds Perform Well, Prompting Early End For Congo Study
August 13, 2019
By Neozene

This article originally appeared in FierceBiotech and was written by Amirah Al Idrus In a world where clinical trials are often stopped due to patient deaths, safety issues or because the drug is likely to fail, an Ebola study in central Africa is ending early for the opposite reason. Investigators stopped a study testing experimental Ebola treatments from Gilead Sciences, Regeneron and the National Institutes of Health because the latter two drugs beat ZMapp, another unapproved drug that had been used in previous outbreaks. The PALM study kicked off in November

Read More