CRISPR Controls Obesity in Mice by Amplifying Rather Than Editing Genes
December 18, 2018
By Neozene

The genes SIM1 and MC4R regulate food intake by signaling the feeling of being full, which is why mutations in those genes are associated with severe obesity. Even if just one of the two copies of those genes that a person inherits from both parents is bad, he or she will most likely feel hungry all the time. What if the one working copy of a satiety-promoting gene could be turbocharged in some way to make up for the lack of functionality of the mutated copy? Scientists at the University

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Tackle The Underlying Cause Of Diabetes
December 12, 2018
By Neozene

Most current diabetes treatments, from insulin injections to newer GLP-1 agonists, don’t solve the underlying cause of the disease. The ability to regenerate insulin-producing cells in the pancreas would do the job, but that has so far proven to be an elusive target. A team of Stanford University scientists is now searching for a solution in a common nutrient: zinc. As it turns out, insulin-producing beta cells have a particularly strong taste for zinc. The researchers are leveraging that affinity to zinc as a way to guide regenerative medicine towards

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